Inflammation, Stress, Physiological, Stress, Psychological
Conditions
Brief summary
The purpose of the study is to determine whether a five day mindfulness retreat in nature can increase measures of attention and self-compassion, and reduce stress among bachelor students at Danish Universities and University Colleges. Secondary whether the expression of inflammatory markers can be reduced . It is the hypothesis that perceived stress is reduced and the expression of genetic markers of inflammation is reduced after a five day mindfulness retreat.
Interventions
BEHAVIORALMindfulness
Five days MBSR curriculum with meditation and yoga
Sponsors
University of Copenhagen
University of Aarhus
VIA University College
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Bachelor student at a Danish University or University College * A score of 16 or above on the Perceived Stress Scale (PSS)
Exclusion criteria
* Smoking * Psychiatric diagnosis (depression, anxiety, adjustment disorder, PTSD, personality disorder, psychosis). * Untreated ADHD, autism, abuse and risk of suicide
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Perceived Stress Scale | At the end of five days retreat | PSS |
| Self-compassion | At the end of five days retreat | S-C-S Neff2 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| NF-kB gene expression | At the end of five days retreat | — |
| IL-1 gene expression | At the end of five days retreat | — |
| IL-6 gene expression | At the end of five days retreat | — |
| cRP expression | At the end of five days retreat | c reactive protein |
| Heart Rate Variability | At the end of five days retreat | HRV |
| Blood pressure | At the end of five days retreat | — |
| Connectedness to Nature Scale | At the end of five days retreat | — |
| GR gene expression | At the end of five days retreat | — |
| RIPK2 gene expression | At the end of five days retreat | — |
| TNF-α gene expression | At the end of five days retreat | — |
| CCL5 gene expression | At the end of five days retreat | — |
| IL-8 gene expression | At the end of five days retreat | — |
| Five Facet Mindfulness Questionnaire | At the end of five days retreat | — |
| TERC gene expression | At the end of five days retreat | — |
| IL-1β protein expression | At the end of five days retreat | — |
| IL-2 protein expression | At the end of five days retreat | — |
| IL-4 protein expression | At the end of five days retreat | — |
| IL-6 protein expression | At the end of five days retreat | — |
| IL-8 protein expression | At the end of five days retreat | — |
| IL-10 protein expression | At the end of five days retreat | — |
| IL-12p70 protein expression | At the end of five days retreat | — |
| IL-13 protein expression | At the end of five days retreat | — |
| TNF-α protein expression | At the end of five days retreat | — |
| IFN-γ protein expression | At the end of five days retreat | — |
| TERT gene expression | At the end of five days retreat | — |
| Breath Counting | At the end of five days retreat | Behavioral measurement of attention |
Countries
Denmark
Outcome results
None listed