Dose-response Effects of Soybean Oil in Salad Dressing on Carotenoid/Fat-soluble Vitamin Bioavailability in Salad Vegetables

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02867488

Enrollment

Unknown

Registered

2016-08-16

Start date

2009-04-30

Completion date

2016-06-30

Last updated

2016-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biological Availability

Keywords

carotenoids, phylloquinone, tocopherols, vitamin A

Brief summary

The objectives will be to evaluate the dose-response between the amount of soybean oil in salad dressing and the absorption of: 1) carotenoids, phylloquinone, and tocopherols in salad vegetables; 2) retinyl palmitate formed from the provitamin A carotenoids, alpha- and beta-carotene.

Interventions

OTHERSoybean oil in salad dressing

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Inclusion criteria

* General good health as determined by interview, blood biochemistry profile, complete blood count, and plasma lipid and lipoprotein profile

Exclusion criteria

* Cigarette smoking, frequent alcohol consumption * Use of vitamin/mineral supplements * Lactose intolerance * Known food allergies * Body mass index (BMI) 30 or higher * Eating disorder or restrained eating * Vegetarianism * Hyperlipidemia * Current or planned pregnancy * Use of hormonal contraceptives (affects chylomicron clearance); use of plant sterols or medications known to affect lipid metabolism

Design outcomes

Primary

Measure	Time frame
Area under the curve for carotenoids, phylloquinone, tocopherols, and retinyl palmitate in the plasma chylomicron fraction	0-9.5 hours postprandially

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 9, 2026