Breast Cancer
Conditions
Brief summary
The association between ultrasound-guided Pecs II block and parasternal block can represent a valid alternative in the management of acute and postoperative pain syndrome after quadrantectomy with or without axillary dissection.
Detailed description
The combination of Pecs II block and PaB provides good management of postoperative pain and can be considered a viable alternative to common anesthetic procedures performed for breast cancer surgery.
Interventions
Pecs II block was performed at the level of the fourth rib in the fascial plane between the minor pectoral and serratus anterior muscles, and 20 ml of 0.5% levobupivacaine solution were injected. An ultrasound-guided ipsilateral parasternal block was performed via two separate injections of 4 ml of 0.375% levobupivacaine at the level of the 2nd and 4th intercostal space underneath the external intercostal membrane between the major pectoral and intercostal muscles close to the surface of the 2nd and 4th rib.
Sponsors
Study design
Eligibility
Inclusion criteria
* 18-75 years of age; * American Society of Anesthesiologists (ASA) physical status I-III, * patients scheduled for quadrantectomy with or without axillary dissection
Exclusion criteria
* pregnancy; * body mass index (BMI) \>35; * allergy to local anesthetics; * skeletal or muscle abnormalities of the chest wall; * presence of primary or secondary neurological diseases; * presence of psychiatric diseases; * history of chronic pain or neuropathic disorders; * history of drug abuse; * state of sepsis; * infection * tumors of the skin on the chest; * primary; * secondary coagulopathies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain | Pain was recorded at 24 months after surgery | Pain has been evaluate with visual analogue scale (VAS) at 24 months after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Neuropathic postoperative disturbances | Neuropathic postoperative disturbances were recorded at 24 months after surgery | Neuropathic postoperative disturbances were examined using the von Frey hair test (neuropathic disturbances: present/not present) at 24 months |
| Patient satisfaction | Patient satisfaction was evaluated at 1 day after surgery | Patient satisfaction with regard to the anesthetic procedure was assessed using a five-step satisfaction scale (not at all/slightly/somewhat/very/extremely satisfied). |
| Woud healing | Wound healing was assessed at 24 months after surgery | Wound healing was assessed using a three-step scale (unacceptable/acceptable/excellent healing) in accordance with the surgeon's opinion. |