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Pecs II Block and PaB Could be an Alternative in Breast Surgery

Association Between Ultrasound-guided Pecs II Block and Parasternal Block May Represent a Valid Alternative for the Management of Acute and Postoperative Pain Syndrome in Breast Cancer Surgery: a Retrospective Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02865265
Enrollment
180
Registered
2016-08-12
Start date
2013-03-31
Completion date
2015-12-31
Last updated
2016-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Brief summary

The association between ultrasound-guided Pecs II block and parasternal block can represent a valid alternative in the management of acute and postoperative pain syndrome after quadrantectomy with or without axillary dissection.

Detailed description

The combination of Pecs II block and PaB provides good management of postoperative pain and can be considered a viable alternative to common anesthetic procedures performed for breast cancer surgery.

Interventions

PROCEDUREPecs II and parasternal blocks

Pecs II block was performed at the level of the fourth rib in the fascial plane between the minor pectoral and serratus anterior muscles, and 20 ml of 0.5% levobupivacaine solution were injected. An ultrasound-guided ipsilateral parasternal block was performed via two separate injections of 4 ml of 0.375% levobupivacaine at the level of the 2nd and 4th intercostal space underneath the external intercostal membrane between the major pectoral and intercostal muscles close to the surface of the 2nd and 4th rib.

Sponsors

Emiliano Petrucci
Lead SponsorOTHER

Study design

Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* 18-75 years of age; * American Society of Anesthesiologists (ASA) physical status I-III, * patients scheduled for quadrantectomy with or without axillary dissection

Exclusion criteria

* pregnancy; * body mass index (BMI) \>35; * allergy to local anesthetics; * skeletal or muscle abnormalities of the chest wall; * presence of primary or secondary neurological diseases; * presence of psychiatric diseases; * history of chronic pain or neuropathic disorders; * history of drug abuse; * state of sepsis; * infection * tumors of the skin on the chest; * primary; * secondary coagulopathies

Design outcomes

Primary

MeasureTime frameDescription
PainPain was recorded at 24 months after surgeryPain has been evaluate with visual analogue scale (VAS) at 24 months after surgery

Secondary

MeasureTime frameDescription
Neuropathic postoperative disturbancesNeuropathic postoperative disturbances were recorded at 24 months after surgeryNeuropathic postoperative disturbances were examined using the von Frey hair test (neuropathic disturbances: present/not present) at 24 months
Patient satisfactionPatient satisfaction was evaluated at 1 day after surgeryPatient satisfaction with regard to the anesthetic procedure was assessed using a five-step satisfaction scale (not at all/slightly/somewhat/very/extremely satisfied).
Woud healingWound healing was assessed at 24 months after surgeryWound healing was assessed using a three-step scale (unacceptable/acceptable/excellent healing) in accordance with the surgeon's opinion.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026