Comparison of the Clinical Efficacy of 2 Paravertebral Block Strategies in Thoracic Surgery by Thoracotomy: by the Anesthetist (Paravertebral Block Guided by Ultrasound) and by the Thoracic Surgeon (Paravertebral Block Visual)

Comparison of the Clinical Efficacy of 2 Paravertebral Block Strategies in Thoracic Surgery by Thoracotomy: : by the Anesthetist (Paravertebral Block Guided by Ultrasound) and by the Thoracic Surgeon (Paravertebral Block Visual)

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02865226

Acronym

PVBS-USguided

Enrollment

Registered

2016-08-12

Start date

2016-08-16

Completion date

2021-09-01

Last updated

2025-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Keywords

thoracic surgery, thoracotomy

Brief summary

Post-thoracotomy pain is one of the most severe. The local analgesia allows its effective control and a reduction of postoperative morbidity and mortality. The gold standard for local analgesia is the thoracic epidural. However, this technique can be dangerous with severe complications. The paravertebral block showed comparable efficacy to the thoracic epidural for local analgesia . In addition, it has a better safety profile. There are several installation techniques. The difference in efficiency of these laying techniques is unknown.

Detailed description

Compare the clinical effectiveness of two strategies of realization of paravertebral block: by the anesthetist before incision (paravertebral block guided by ultrasound) and by the thoracic surgeon at chest closure (paravertebral block visual).

Interventions

OTHERparavertebral block by the anesthetist before incision (paravertebral block guided by ultrasound)

OTHERparavertebral block by the thoracic surgeon at chest closure (paravertebral block visual).

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patient with thoracotomy indication for segmentectomy (s), lobectomy (s) lung or pulmonary wedge resection * patient consenting to participate to the study * patient enrolled in the national healthcare insurance program * patient older than 18 years

Exclusion criteria

* patient with neuropathy * patient with body mass index superior to 35 kg/m2 * patient with contraindication for paravertebral block or local analgesia

Design outcomes

Primary

Measure	Time frame	Description
pain	24 hours	Pain evaluated using a visual analog pain scale

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026