Anesthesia, Diabetes, Hypertension
Conditions
Brief summary
The aim of this observational study is to create a data base to extract feature of fast-acting drugs that can be monitor in real time to design control strategies based on high order sliding mode controller to create a robust drug infusion system.
Detailed description
The aim of this observational study is to create a database to extract feature of fast-acting drugs that can be monitor in real time to design control strategies based on high order sliding mode controller to create a robust drug infusion system. The observed drugs in this study are fast acting insulin, propofol and sodium nitroprusside. The effect of insulin will be measured by a continuous glucose monitor, the effect of propofol by a bispectral index monitor and the the effect of sodium nitroprusside by a invasive blood pressure monitor.
Interventions
None listed
Sponsors
Coordinación de Investigación en Salud, Mexico
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anesthesiologists (ASA) physical status I, II, II
Exclusion criteria
* Impossibility to measure depth of anesthesia or invasive blood pressure. Impossibility of using glucose monitor.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Glucose | Every 5 minutes during 3 days. | The glucose will be measured by a continuous glucose monitor. For the group of patients for diabetes. Note: This protocol has three primary outputs because its objective is to create a database of each output to analyze the response to the associated drug (insulin, propofol and sodium nitroprusside. |
| Bispectral Index | Every second during surgery | Depth of anesthesia will be measured by a Bispectral Index monitor. |
| Invasive blood pressure | Every 5 minutes during surgery | — |
Countries
Mexico
Outcome results
None listed