Cavernous Sinus Dissection and Bleeding in Meningiomas

Dissection of the Outer Layer of the Lateral Wall of the Cavernous Sinus Decreases Bleeding as Compared to Direct Tumor Attack in Middle Fossa Meningiomas: A Randomized Controlled Trial

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02863484

Acronym

OCS

Enrollment

120

Registered

2016-08-11

Start date

2016-05-31

Completion date

2016-10-31

Last updated

2016-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meningiomas of the Middle Cranial Fossa

Brief summary

The blood loss will be compared in middle fossa meningiomas which will receive pealing of the outer layer of the lateral wall of the cavernous sinus and those which will not revive pealing before the dura is opened

Detailed description

Cases with middle fossa meningiomas will be randomised to one of two surgical techniques. The first technique will involve pealing of the outer layer of the lateral wall of the cavernous sinus before the dura is opened and the tumour attacked, and the second group of cases will be operated by a standard technique, where the tumour will be directly attacked with out pealing of the outer layer of the lateral wall of the cavernous sinus. Blood loss will be monitored in each case by calculating the amount of blood in the suction container and subtracting it from the amount of fluids used for irrigation during surgery. The number of cotton patties and dressings will be also counted with each case as well as the number of gauzes used. The pre-operative complete blood picture will be documented particularly the haemoglobin , hematocrits and others. The same lab data will be also monitored after surgery. The amount of blood transfusion required will also be calculated in each case.

Interventions

OTHERsurgery

pealing of the outer layer of the cavernous sinus

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Meningiomas of the middle cranial fossa

Exclusion criteria

* Meningiomas outside the middle cranial fossa

Design outcomes

Primary

Measure	Time frame
Amount of blood loss as estimated by cubic centimetres during surgery	three months

Secondary

Measure	Time frame
Radically of surgery as estimated by post-operative tumour volume in cubic centimetres on post-operative MRI	3 months

Countries

Egypt

Contacts

Primary ContactAhmed A Hegazy, MD

ahmed.hegazy@kasralainy.edu.eg01002155090

Backup ContactNoha Asem, MD

kasralainirec@yahoo.com01003657120

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026