Neoplasms, Germ Cell and Embryonal
Conditions
Brief summary
Retrospective and prospective cohort of patients with germ cell tumor in treatment.
Detailed description
The primary objective of this study is to create a multicenter database in order to characterize epidemiologically and clinicopathologically patients with germ cell tumor and evaluate the prognosis and clinical outcomes during cancer treatment.
Interventions
None listed
Sponsors
Latin American Cooperative Oncology Group
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Male patients with diagnosis of testicular, retroperitoneum or mediastinal primary tumor. * Histological confirmation of germ cell tumor or clinical condition based on the elevation of tumor markers (AFP, HCG e/ou DHL) associated to testicular mass or/and retroperitoneal lymphnode enlargement or/and mediastinal mass. * Medical records of the disease and treatment
Exclusion criteria
* Female patients diagnosed with ovary germ cell tumor * Male patients diagnosed with germ cell tumor in other locations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brazilian multicenter database in order to collect and analyze data from diagnosis and treatment of patients with germ cell tumor | From 2000 to 2025 |
Secondary
| Measure | Time frame |
|---|---|
| Treatment according to staging and relapse of patients diagnosed with testicular germ cell tumor in Brazil | From 2000 to 2025 |
| Disease free survival of patients diagnosed with germ cell tumor stage 1. | From 2000 to 2025 |
| Overall survival of patients diagnosed with germ cell tumor stage 1. | From 2000 to 2025 |
| Disease free survival of patients diagnosed with germ cell tumor stages 2 and 3. | From 2000 to 2025 |
| Overall survival of patients diagnosed with germ cell tumor stages 2 and 3. | From 2000 to 2025 |
| The clinical and pathological characteristics of testicular germ cell tumor patients in Brazil. | From 2000 to 2025 |
| International prognostic factors in patients with advanced germ cell tumor (stages 2 and 3) stablished by the International Germ Cell Cancer Collaborative Group in brazilian patients. | From 2000 to 2025 |
| Treatment outcome in different populations: in patients with brain metastasis, patients with germinative tumor extragonodal, surgery outcome in patients with nonseminomous tumor and ressection of residual lesion after chemotherapy | From 2000 to 2025 |
| Disease free survival of patients diagnosed with disease relapse after first line chemotherapy | From 2000 to 2025 |
| Overall survival of patients diagnosed with disease relapse after first line chemotherapy | From 2000 to 2025 |
| Prognostic model after first line treatment failure with cisplatin, stablished by the International Prognostic Factors Study Group in brazilian patients. | From 2000 to 2025 |
| Description of demographic characteristics of testicular germ cell tumor patients in Brazil | From 2000 to 2025 |
Countries
Brazil
Outcome results
None listed