Breast Cancer, Fertility
Conditions
Keywords
Breast cancer, Fertility
Brief summary
To evaluate the attitude of pre menopausal women with breast cancer faced with the risk of loss of fertility caused by chemotherapy using EORTC's Fertility Questionnaire.
Detailed description
To characterize the attitude of pre menopausal patients with breast cancer regarding the risks of infertility based on the following variables: * Age at diagnosis * Number of children * Will of having children * Marital status * Scholarity * Period of time from the diagnosis * Time of the last menstruation period * Chemotherapy administration * Clinical staging at the diagnosis * Pathological evaluation * Documentation of the cancer therapy
Interventions
None listed
Sponsors
Grupo de Estudios Clínicos Oncológicos Peruano
Latin American Cooperative Oncology Group
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Women with age ≥ 18 and ≤ 40 * Indication of (neo) adjuvant chemotherapy * Prior chemotherapy treatment * Patients with menstrual periods in the last 6 months * In use of contraceptive methods * Without breast cancer recurrence * Capacity to read and understand the informed consent
Exclusion criteria
* Patients which received or with indication of definitive ovarian suppression (surgery and/or radiotherapy), except temporary pharmacological ovarian suppression * Patients whom initiated chemotherapy treatment before entering the study * Altered state of mind, dementia, or any other psychiatry problem that can interfere in the comprehension or interpretation of the informed consent. * Previous diagnosis of infertility
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To analyze the number of pre-menopausal patients diagnosed with breast cancer that did not agree in receiving chemotherapy due to the risk of infertility | Baseline and 1 year after after the first interview |
Secondary
| Measure | Time frame |
|---|---|
| Minimal percentage of cure necessary for patients accept the chemotherapy treatment | Baseline and 1 year after the first interview |
| Age when diagnosed | Baseline and 1 year after the first interview |
| Number of children | Baseline and 1 year after the first interview |
| Desire to have kids | Baseline and 1 year after the first interview |
| Marital status | Baseline |
| Infertility risk for breast cancer patients after accepting chemotherapy | Baseline and 1 year after the first interview |
| Period of time since the diagnosis | Baseline |
| Chemotherapy scheme administration | Baseline and 1 year after the first interview |
| Period of time from the last menstruation period | Baseline and 1 year after the first interview |
| Description of quality of life of patients with the EORTC QLQ-BR23 | Baseline and 1 year after the first interview |
| Scholarity | Baseline |
Countries
Brazil, Cuba, Mexico, Peru, Venezuela
Outcome results
None listed