Gastro entérite
Conditions
Brief summary
Cosavirus and Salivirus are two new genera of Picornaviridae and are responsible for acute diarrhoea. They have been identified in the pathological stools of infants and immuno-compromised subjects on every continent with prevalences ranging from 2.8% to 8.8% depending on the virus, the cohort and the country studied. To date, no study on these two viruses has been conducted in France to evaluate the circulation and the pathogenicity of these viruses in subjects with diarrhoea. The aim of this study is thus to: * show that these viruses are in circulation in France in infants younger than 5 years old and that the proportions are similar to those reported in the literature. * confirm the relationship between the diarrhoea and the infection with these viruses.
Interventions
OTHERstool samples
Sponsors
Centre Hospitalier Universitaire Dijon
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 5 Years
Healthy volunteers
Yes
Inclusion criteria
* Children younger than 5 years * Children hospitalized or consulting at Dijon CHU during the 12 months of the study for acute gastroenteritis. Acute gastroenteritis is defined by at least 3 soft or liquid stools or at least 3 bouts of vomiting within 24 hours or signs (diarrhoea or vomiting) accompanied by at least 2 additional symptoms among diarrhoea or vomiting, abdominal pain, fever for controls * Children younger than 5 years old * Children hospitalized or consulting at Dijon CHU during the 12 months of the study for any illness without diarrhoea (other than
Exclusion criteria
).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of viruses detected | Baseline |
Countries
France
Outcome results
None listed