Uric Acid Levels and Endothelial Functions

Clinical Follow-up of Patients With Assessment of Endothelial Dysfunction/Coronary Spasm

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02862522

Enrollment

229

Registered

2016-08-11

Start date

1992-01-31

Completion date

2016-02-29

Last updated

2016-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

uric acid, microvascular dysfunction, inflammation

Brief summary

Uric acid is a risk factor for coronary artery disease (CED) in postmenopausal women but the association with inflammation and coronary microvascular endothelial dysfunction is not well-defined. The aim of this study was to determine the relationship of serum uric acid, inflammatory markers and CED.

Interventions

OTHERQuestionnaire of overall health

The standardized questionnaire was used to assess occurrence of major adverse cardiovascular events including stroke, re-hospitalization, myocardial infarction or death. Responses were verified by medical record review conducted by an investigator blinded to the results of the standardized questionnaire.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

50 Years to No maximum

Healthy volunteers

Inclusion criteria

* Referred to Mayo Clinic for cardiac catheterization * Postmenopausal

Exclusion criteria

* History of percutaneous coronary intervention * Coronary artery bypass graft surgery * Unstable angina pectoris * Valvular heart disease * Peripheral vascular disease * Known congestive heart failure

Design outcomes

Primary

Measure	Time frame
Serum Uric Acid Level	Baseline

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026