Bone Health in Hyperemesis Gravidarum

Urine N-telopeptide, Serum Vit D, Parathormone and Calcium Levels in Hyperemesis Gravidarum

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02862496

Enrollment

Registered

2016-08-11

Start date

2016-06-30

Completion date

2016-10-31

Last updated

2016-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperemesis Gravidarum

Keywords

Hyperemesis Gravidarum, Bone Health, Urine N-telopeptide, Serum calcium, Serum parathormone, Serum vit D

Brief summary

The purpose of the study is to determine whether maternal bone resorption would be seen in Hyperemesis Gravidarum and could be detected in early period using serum vitamin D levels, serum calcium (Ca) levels, serum parathormone (PTH) levels and urine N- telopeptide levels in the patients with Hyperemesis Gravidarum.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* Between 7. and 20. weeks of gestation pregnant women in both groups * İn hyperemesis group; 5% weight loss with regard to pre-gestation vomiting more than 3 times 3-5 % weight loss with ketonuria.

Exclusion criteria

* Other pathologies that cause nausea and vomiting in pregnancy gastroenteritis gastroparesis gall duct diseases hepatitis peptic ulcers appendicitis pyelonephritis ovarian torsion urinary tract stones diabetic ketoacidosis hyperthyroidism hyperparathyroidism migraine pseudo tumor cerebra vestibular diseases * Additionally some situations causing to rise of Ntx levels osteoporosis paget disease bone tumors * Furthermore some of conditions resulted in pre-menopausal osteoporosis or decreasing in Bone Mineral Density Malignancy Smoking Celiac Disease Depression Inflammatory Bowel Disease Pre-gestational Diabetes Chronic Kidney or Liver Disease Drug Use such as steroids, anticonvulsants, antiepileptic, heparin or low molecular weight heparin

Design outcomes

Primary

Measure	Time frame
Urine N- telopeptide levels in Pregnant Women with Hyperemesis Gravidarum	4 months
Serum Vitamin D Levels in Pregnant Women with Hyperemesis Gravidarum	4 months
Serum Calcium Levels in Pregnant Women with Hyperemesis Gravidarum	4 months
Serum Parathormone Levels in Pregnant Women with Hyperemesis Gravidarum	4 months

Countries

Turkey (Türkiye)

Contacts

Primary ContactErdem SAHİN, Study Principal İnvestigator

erdemsahin07@hotmail.com+905321688683

Backup ContactYusuf MADENDAG

yusufmadendag@gmail.com+905055011340

Outcome results