Skip to content

Perception of Objects and Natural Scenes in People With Vision Loss (ACTIVIS)

Evaluation of the Perception of Objects and Natural Scenes in People With Vision Loss (Loss of Central or Peripheral Vision)

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02862405
Acronym
ACTIVIS
Enrollment
260
Registered
2016-08-11
Start date
2011-03-31
Completion date
2015-03-31
Last updated
2016-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vision Loss

Keywords

Vision loss, Object recognition, Space recognition

Brief summary

The loss of central vision causes difficulty not only in reading but also in faces recognition, and in particular in the identification of facial expression, objects or spaces. These visual deficits have been mainly studied in relation with reading, which is the main complaint of these kind of patients. However, there are not enough data regarding perception of objects and spaces in this population. Then, the objectives are to study the visual-spatial abilities in individuals with vision loss, and altered cognitive processes, (2) to develop clinics tools for early detection and quantification of visual-spatial deficits and (3)to understand the capacities of normal peripheral vision in order to test the possibility of potential training for use of peripheral vision when central vision is impaired by an ophthalmic pathology.

Interventions

Sponsors

University Hospital, Lille
CollaboratorOTHER
Lille Catholic University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes

Inclusion criteria

cases: * Patients with eye disease causing loss of central or peripheral vision * French speakers * Age between 18 and 90 years old * Written consent * Health insurance Inclusion Criteria controls: * Sex and age matched controls (+/- 5 years) * French speakers * Normal visual examination with visual acuity of min 9/10

Exclusion criteria

* Psychiatric disease or neurological pathologies * Communication difficulties (deafness / mutism) * Drug treatment altering concentration * Mental deterioration with MMS \<24 * Alcoholism or addiction to drugs * Persons under guardianship

Design outcomes

Primary

MeasureTime frameDescription
Comparison of performances in visual tests between different groups according to error rateat inclusionThese behavioral studies include a series of short tests of 5 to 10 minutes each (not exceeding 60 minutes with breaks and instructions) in which photos of scenes or isolated objects will be presented in central or peripheral vision using a computer screen or a panoramic screen covering a 180° field.
Comparison of performances in visual tests between different groups according to answer timeat inclusionThese behavioral studies include a series of short tests of 5 to 10 minutes each (not exceeding 60 minutes with breaks and instructions) in which photos of scenes or isolated objects will be presented in central or peripheral vision using a computer screen or a panoramic screen covering a 180° field.

Secondary

MeasureTime frameDescription
Estimation of the score of visual acuity by the logMAR chartat inclusion
Measure of lesion sizeat inclusion
Pearson correlation coefficient to determine the correlation between the performance parameters during visual tests (error rate and answer time) and clinical parameters (visual acuity and lesion size)at inclusionThese behavioral studies include a series of short tests of 5 to 10 minutes each (not exceeding 60 minutes with breaks and instructions) in which photos of scenes or isolated objects will be presented in central or peripheral vision using a computer screen or a panoramic screen covering a 180° field.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026