Inflammatory Bowel Diseases, Keratoconus
Conditions
Brief summary
A retrospective study has shown the association between the inflammatory bowel diseases (IBD) and the presence of a keratoconus. This new study will measure the prevalence of keratoconus and follow its activity in patients affected by IBD and followed up in hepatology-gastroenterology department at Nancy Hospital. The prevalence of keratoconus will be compared to known data of literature about general population. The secondary purpose is to search for a relationship between the presence of a keratoconus and activity criteria of IBD. Perspectives are a systematic screening for keratoconus in patients affected by IBD with the amelioration of the ophthalmologic care of IBD patients and confirmation of the recent hypothesis of inflammatory origin of keratoconus.
Interventions
DEVICEOpthalmologic measure with DM OPD scan III (Nidek)
Bilateral measure of corneal refractometry, pachymetry, topography and aberrometry
Sponsors
Central Hospital, Nancy, France
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Informed consent * Affiliation to social security plan * Diagnosis of IBD since more than 3 years, under treatment or not
Exclusion criteria
* Protected person * Pregnant or breastfeeding women * Person in life-and-death emergency * Person deprived of liberty * Refusal to remove contact lenses, where necessary
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Absence or presence of keratoconus in IBD patients | day 0 | Data from OPD scan III corneal analyzer according to Rabinowitz and Klyce Maeda criteria. The presence of a keratoconus in at least one eye is considered positive. |
Secondary
| Measure | Time frame |
|---|---|
| IBD clinical features using the Montreal classification for IBD | day 0 |
Outcome results
None listed