The Sweat Alcohol Concentration
Conditions
Brief summary
A non invasive transdermal sensor device was developed by the Im2Np laboratory to determine the presence of vapor of alcohol in insensible perspiration. One of possible application would be a continuous and non invasive monitoring of drinking behavior. To investigate the validity of this method, it's necessary to compare Transdermal Alcohol Concentrations results obtained by this new device with Blood Alcohol Concentrations and breath Alcohol Concentrations provided by reference methods. The purpose of this study is to identify the kinetic of alcohol concentration in blood, exhaled air and sweat after alcohol ingestion.
Interventions
OTHERoral dose of alcohol
DEVICEalcotest
BIOLOGICALblood samples
DEVICETransdermal monitor
Sponsors
Assistance Publique Hopitaux De Marseille
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Male or female 18-40 years, age-matched (+ 3 years) * Caucasian * BMI: 19 to 28 kg/m2 * No smoking or light smoker (\<5 cig/d) * Moderate consumer of alcohol (3-14 drinks/week), with the intoxicated experience
Exclusion criteria
* Subjects with addiction to toxic or alcohol (MINI Questionnaire) * Positive individuals in search of drugs and toxic * Anxiety or depressive subjects (IASTA Questionnaires and BDI)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The determination of ethanol in the plasma | 6 months | blood samples |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| measures in the exhaled air | 6 months | Assessed with the device Alcotest® |
| sweat alcohol concentration | 6 months | assessed with a Transdermal monitor |
Outcome results
None listed