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Continuous Versus Intermittent Oxytocin for Induction of Labor: A Randomized Study

Status
UNKNOWN
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02859571
Enrollment
200
Registered
2016-08-09
Start date
2016-08-31
Completion date
2017-01-31
Last updated
2016-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intemittant, Continue, Oxytocin

Brief summary

This study evaluates continuous oxytocin versus intermittent oxytocin for induction of labor at term. Half of participants will be taken continuous oxytocin, while the other half will be taken intermittent oxytocin.

Detailed description

In the continuous oxytocin group, traditional treatment of oxytocin used at a starting dose of 1-2 mIU/min and the dose was increased by 2 mIU/min at every 15 minutes until regular contractions obtained at a rate of 3-5 contractions in a 10-minute period. The maximum dose of oxytocin was 40 mIU/min and oxytocin was administered until delivery. In the intermittent group, oxytocin was discontinued when cervical dilation was 5 cm and 2 hours after discontinuation oxytocin was reused at a starting dose of 1-2 mIU/min and was increased as the same protocol used for continuation oxytocin group.

Interventions

DRUGOxytocin

Sponsors

Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* singleton pregnancy, * 37≤ weeks of gestational age , * vertex presentation, * women with cervical dilation 3 cm * no contraindication to vaginal delivery.

Exclusion criteria

* fetal malpresentation, * multifetal pregnancy, * more than three contractions in 10 minutes, * contraindications to oxytocin, * a category II or III fetal heart rate pattern, * fetal anomaly, * fetal demise * women with immediate delivery indications

Design outcomes

Primary

MeasureTime frame
induction-to-delivery timeintraoperative

Countries

Turkey (Türkiye)

Contacts

Primary Contactevrim bostanci ergen, M.D.
evrimbostanc6666@gmail.com505 617 96 23

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026