Skip to content

The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary Oxygenation in Lung Transplantation Patients

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02859194
Enrollment
10
Registered
2016-08-08
Start date
2016-05-31
Completion date
2016-10-14
Last updated
2018-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ARDS (Acute Respiratory Distress Syndrome), Bronchiectasis, COPD (Chronic Obstructive Pulmonary Disease), Interstitial Pulmonary Fibrosis ARDS, Lymphangioleiomyomatosis, Primary Pulmonary Hypertension

Brief summary

ECMO(Extracorporeal membrane oxygenation) is being essential for cardiopulmonary failure patients. There are two types of ECMO, which is veno-veno (V-V) that can be used in respiratory failure patients and veno-arterial (V-A) that can be used in cardiac failure patients. V-A ECMO can also be used during lung transplantation, substitution of cardiopulmonary bypass, which can show sufficient performance during operation and better postoperative outcome. However, regarding V-A ECMO circulating from femoral vein to femoral artery, there is a pro blem of differential hypoxia which might influence coronary artery and head vessels. In this prospective study, the investigators are planning to put another ECMO catheter into internal jugular vein which takes a role of left to right shunt, to mitigate the hypoxia of coronary artery.

Interventions

PROCEDUREVeno-veno-arterial ECMO

Sponsors

Yonsei University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

1\. scheduled for double lung transplantation

Exclusion criteria

1. patients who have history of coronary artery occlusive disease 2. patients with arrhythmia

Design outcomes

Primary

MeasureTime frame
arterial blood oxygen partial pressure (PaO2)5 min after jugular catheter flow 0ml/min

Secondary

MeasureTime frame
venous blood oxygen partial pressure (PvO2)5 min after jugular catheter flow 0ml/min

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026