Diabetes
Conditions
Keywords
Metabolic diseases
Brief summary
The purpose of this study is to help scientists understand how the gut senses ingested nutrients and what kind of processes take place for their absorption in order to establish the association with diabetes and other metabolic diseases Scientists need human specimens to study.
Interventions
PROCEDURECollection of digestive tissues
The surgeon will resect a sample (approximately 1-5 cm x 1-5 cm) of healthy tissue from the distal margins of the segment and at least 4 cm from the diseased area. The specimen for research will be obtained from the tissue that would ordinarily be removed during surgery.The tissue collected for our research purposes will be only remnant tissue which is discarded by the surgeon during the surgical intervention and has no diagnostic clinical value.
Sponsors
AdventHealth Translational Research Institute
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Men and women age 18 years and older who are having elective gastrointestinal surgery 2. Able to provide written, informed consent
Exclusion criteria
1. Unable to provide written, informed consent 2. Use of antibiotics for more than 5 consecutive days in the three months prior to the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tissue collection | Day of surgery | During surgery, a tissue specimen that would normally be discarded, will be obtained and used to identify the localization and amount of different proteins that regulate nutrient absorption. |
Countries
United States
Outcome results
None listed