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Improving the Diagnosis of Tonsillitis in Emergency Rooms

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02858687
Enrollment
312
Registered
2016-08-08
Start date
2013-02-26
Completion date
2022-10-27
Last updated
2023-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tonsillitis

Brief summary

A point-of-care laboratory (POC) was set at North Hospital, Marseille, France for the diagnosis in less than two hours of tonsillitis caused by known pathogens, close to the reception of Emergency service. In this instance 30% of patients have no etiological diagnosis after the POC tonsillitis tests . This lab has discovered over 200 new species of bacteria in humans, including vector bacteria and opened the field of large Deoxyribonucleic Acid (DNA ) viruses. Also, the laboratory of emerging viruses discovered many Ribonucleic Acid (RNA) viruses transmitted by arthropods. Based on this collection of new pathogens described in POC laboratory, this study proposes to expand the etiological diagnosis strategy of tonsillitis after POC tests. The objective of this study is to implement a new diagnosis strategy relying on the hypothesis that a second pharyngeal swab would improve the etiological diagnosis of tonsillitis of at least 5%.

Interventions

OTHERNasopharyngeal swab

Sponsors

Assistance Publique Hopitaux De Marseille
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patient admitted at hospital for tonsillitis requiring, for the emergency physician, a microbiological examination with a POC tonsillitis kit. * Patient who has freely signed the informed written consent * Patient affiliated to a social security scheme

Exclusion criteria

* Pregnant woman, parturient or nursing * Adult patient under guardianship * Patient deprived of liberty under court order * Patient refusing or unable to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
Percentage of patients admitted for tonsillitis with a confirmed etiological diagnosis of tonsillitis1 day

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026