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Improving the Diagnosis of Meningitis in Emergency Rooms

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02858661
Enrollment
109
Registered
2016-08-08
Start date
2013-03-30
Completion date
2022-10-27
Last updated
2023-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meningitis

Brief summary

A point-of-care laboratory (POC) was set at North Hospital, Marseille, France for the diagnosis in less than two hours of meningitis caused by known pathogens, close to the reception of Emergency service. In this instance 30% of patients have no etiological diagnosis after the POC diarrhoea tests . This lab has discovered over 200 new species of bacteria in humans, including vector bacteria and opened the field of large Deoxyribonucleic Acid (DNA ) viruses. Also, the laboratory of emerging viruses discovered many Ribonucleic Acid (RNA) viruses transmitted by arthropods. Based on this collection of new pathogens described in POC laboratory, this study proposes to expand the etiological diagnosis strategy of meningitis after POC test.

Interventions

OTHERNasopharyngeal swab

Sponsors

Assistance Publique Hopitaux De Marseille
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patient admitted at hospital for meningitis requiring, for the emergency physician, a microbiological examination with a POC meningitis kit. * Patient who has freely signed the informed written consent * Patient affiliated to a social security scheme

Exclusion criteria

* Pregnant woman, parturient or nursing * Adult patient under guardianship * Patient deprived of liberty under court order * Patient refusing or unable to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
Percentage of patients admitted with a meningitis with a confirmed etiological diagnosis1 day

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026