Renal Failure
Conditions
Keywords
pediatric, renal transplant, pain, dual TAB
Brief summary
Alleviating pain in children undergoing renal transplant is extremely challenging. Large incisions as those of renal transplant (Gibson's incision) require special techniques of pain control that don't affect hemodynamics or renal function. Since the transplant incision doesn't cross midline; a dual-TAP block is thought to be effective in providing pain control in such procedure as it will anesthetize the dermatomes T6-T12, the muscles of the anterior abdominal wall together with the underlying parietal peritoneum.
Interventions
DRUGbupivacaine
bupivacaine 0.25% at a dose 2 mg/kg in the transversus abdominis plane
DRUGPethidine
pethidine intravenous at a dose 1mg/kg when pain score more than 5 postoperative rescue analgesia
DRUGperfalgan
intravenous paracetamol
DRUGfentanyl
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
3 Years to 16 Years
Healthy volunteers
No
Inclusion criteria
* 3-16 years * end stage renal disease * no known allergy to bupivacaine * both sexes
Exclusion criteria
* known allergy to bupivacaine
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| total dose of rescue analgesia | from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours | pethidine given as rescue analgesia postoperative. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| pain scoring system (objective behavioural pain score) | from the time of transfer to the nephrology ICU, every hour for the first 24 hours postoperative | — |
| Intraoperative blood pressure | from the induction of anesthesia till end of surgery at half an hour intervals average duration is 4 hours | measure systolic and diastolic blood pressure |
| postoperative blood pressure | from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours | record systolic and diastolic blood pressure every hour for the first 24 hours postoperative |
| postoperative heart rate | from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours | — |
| intraoperative heart rate | from the induction of anesthesia till end of surgery at half an hour intervals average duration is 4 hours | — |
Countries
Egypt
Outcome results
None listed