Depression
Conditions
Keywords
depression, emotional reactivity
Brief summary
The study aimed to determine the emotional reactivity of depressed patients to visual and olfactory stimuli in comparison with healthy volunteers.
Interventions
BEHAVIORALolfactory assessment
determination of olfactory sensitivity through olfactory threshold assessment (butanol) determination of hedonicity and intensity of 16 usual odors
BEHAVIORALimage visualization
20 images (from the IAPS-international affective picture systems) are presented to the subject. He has to determine the hedonicity of each picture.
BEHAVIORALpsychophysiological assessment
during the olfaction assessment and the image visualization, skin conductance reactivity (SCR) is recorded to assess unconscious emotional reactivity
Sponsors
Centre Hospitalier Universitaire de Besancon
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* no cognitive impairment that could prevent instruction comprehension * no more than 10 cigarettes/day * signed informed consent * group 1: current major depressive disorder * group 2: no current major depressive disorder
Exclusion criteria
* pregnancy * visual impairment * olfactory impairment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| hedonicity score of visual stimuli | up to 1 month | it will be compared between depressed and non depressed subjects. |
| skin conductance reactivity amplitude | up to 1 month | it will be compared between depressed and non depressed subjects. |
| Skin conductance reactivity reaction time | up to 1 month | it will be compared between depressed and non depressed subjects. |
| hedonicity score of olfactory stimuli | up to 1 month | it will be compared between depressed and non depressed subjects. |
Countries
France
Outcome results
None listed