Cancer Pain
Conditions
Keywords
methadone, cancer pain, long term effect
Brief summary
The methadone is an useful opioid for the cancer pain treatment, mostly used in second or last line during the opioid rotation. The Methadone had an anti-MNDA effect, and clinicians agree that the methadone could have an effect in neuropathic cancer pain. During a previous study the investigators find that the pain was still improving after the week 2, but they had only a small number of patients still included at this stage and they cannot conclude. The investigators decide to follow up systematically all the patients undergoing a methadone treatment for cancer pain, at day 28, to study the hypothesis about the long-term pain improvement.
Interventions
None listed
Sponsors
Hospices Civils de Lyon
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with t methadone for cancer pain in opioid rotation * Able to fill the questionnaire * Performance status (PS) from 0 to 2
Exclusion criteria
* Patients PS 3 * Unable to sign the informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Difference between EVA pain score at Day 28 and Day 0 | pain score measure at Day 0 and Day 28 | long-term effects of methadone for cancer pain |
Secondary
| Measure | Time frame |
|---|---|
| Change in quality of life score QOL C30 | Day 0 and Day 28 |
| Change in score of neuropathic pain intensity NPSI | Day 0 and Day 28 |
| Change in depression and anxiety score HADS | Day 0 and Day 28 |
| Side effect record | up to Day 28 |
Countries
France
Contacts
Primary ContactMarilene FILBET, Pr Associate
Outcome results
None listed