Appearance of Far Peripheral Retina in Normal Eyes by Ultra-widefield Fluorescein Angiography

The Director of the Fundus Center of Zhongshan Ophthalmic Center

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02856139

Enrollment

Registered

2016-08-04

Start date

2014-11-30

Completion date

2016-01-31

Last updated

2016-08-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Normal Eyes, Peripheral Retina

Keywords

ultra-widefield fluorescein angiography, peripheral retina, normal eyes

Brief summary

Detailed description

PURPOSE: To characterize the appearance of the far peripheral retina of normal eyes using ultra-widefield fluorescein angiography (UWFA). DESIGN: Prospective observational case series. METHODS: This study enrolled normal eyes with best corrected visual acuity ≥ 20/20, refractive error \< 3.00D, and without visible retinal pathologic changes under a slit lamp-based condensing lens. Demographic and clinical data such as age, sex, and reasons for undergoing FA were collected. The far peripheral retina was detected by UWFA. The fundal fields obtained using the Heidelberg ultra-widefield lens in a single shot and in montage images were compared with those acquired using the Heidelberg conventional 55° lens. The signs at the peripheral retina detected by UWFA were described and grouped. Ciliary body thickness (CBT) at 3 mm (CBT1) and 2 mm (CBT2) posterior to the scleral spur was measured by ultrasound biomicroscopy.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 70 Years

Healthy volunteers

Inclusion criteria

* best corrected visual acuity ≥ 20/20 * refractive error \< 3.00D * without visible retinal pathologic changes under a slit lamp-based condensing lens

Exclusion criteria

* history of ocular surgery * presence of ocular or systemic diseases * opacity of refractive media, which interfered with the peripheral retina image quality

Design outcomes

Primary

Measure	Time frame
Ultra-widefield fluorescein angiography findings at the far peripheral retina of normal eyes	from November 2014 to January 2016

Secondary

Measure	Time frame
Ciliary body thickness	from November 2014 to January 2016

Countries

China

Outcome results