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Functional Prognosis in Patients With Ischemic Stroke According to the Therapeutic Strategy Used

Prognosis After Revascularization Therapy in the Dijon Ischemic Stroke Evaluation Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02856074
Acronym
PARADISE
Enrollment
821
Registered
2016-08-04
Start date
2016-01-13
Completion date
2020-06-01
Last updated
2021-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Stroke

Brief summary

The current management of ischemic stroke is based on different strategies that may be combined: intravenous thrombolysis in a stroke ICU, intravenous thrombolysis in a telemedicine procedure, endovascular thrombectomy. Given this now rich therapeutic arsenal, it seems necessary to evaluate practices in local care in the field and the impact of these on the prognosis of ischemic stroke victims. The aim of this observational study is to compare these different care practices without interfering with the choice of strategy. A blood sample will also be taken at different times to study the value of growth differentiation factors (GDF) 8, 11 and 15, and Brain-derived Neurotrophic Factor as prognostic biomarkers

Interventions

BIOLOGICALprise de sang
OTHERquality of life questionnaire

Sponsors

Centre Hospitalier Universitaire Dijon
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients with symptomatic ischemic stroke defined according to WHO criteria and treated by intravenous thrombolysis at the stroke ICU at Dijon CHU, intravenous thrombolysis by telemedicine with subsequent transfer to the Dijon stroke ICU, and/or endovascular thrombectomy at Dijon CHU) * Patients aged over 18 years. * Patients who have provided written informed consent to take part in the study.

Exclusion criteria

* Patients who refuse to take part in the study. * Subjects in custody. * Patients (or a person of trust) who cannot be contacted by telephone during the follow-up.

Design outcomes

Primary

MeasureTime frame
Rate of handicap6 months

Secondary

MeasureTime frame
Serum levels of biomarkers of stressChanges compared with baseline levels at Day 1, Day 3, Day 7

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026