Exercise Training in Patients With Rheumatoid Arthritis and Cryotherapy

Exercise Training in Patients With Rheumatoid Arthritis and Cryotherapy: Feasibility Study

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02855801

Acronym

RhumatEx

Enrollment

Registered

2016-08-04

Start date

2013-06-30

Completion date

2016-12-31

Last updated

2017-02-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arthritis, Rheumatoid

Brief summary

The main objective of this project is to study, in patients with rheumatoid arthritis, the effects of an intermittent type exercise associated with cryotherapy on the level of inflammation during its recovery.

Interventions

OTHERconstant exercise

OTHERcryotherapy

OTHERintermittent exercise

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Men and women \>18 years old, \< 80 years old * Signature of informed consent for participation * Affiliation to a social security scheme or French beneficiary of such a regime. * confirmed rheumatoid arthritis and monitoring by the rheumatology department of the University Hospital of Besancon. * If there is a corticosteroid therapy, it must be stable for at least 1 month and less than or equal to 10 mg of prednisone equivalent per day * Clinical and biological activity will be moderate (ie not in remission and not severe based on Disease Activity Score 28 joints - DAS 28 - to be between 2 and 6 * Patients could be treated with DMARDs (Disease-Modifying Drugs).

Exclusion criteria

* Patient under guardianship, curatorship, under judicial protection, major incapable * Patients whose body mass index (BMI) greater than 30, * Pathology incompatible with the completion of a cycle ergometer exercise (heart, vascular, respiratory, orthopedic ...) * Change in DAS28 greater than 1.2 in the previous 3 months Inclusion * A patient with a DAS28 \> 6 * about the cold: Raynaud's syndrome, cold known allergy, sickle cell anemia, cryoglobulinemia, uncontrolled hypertension * Patient unable to follow protocol because of cognitive, psychiatric or language difficulties. * Inability to follow protocol for causes related to health problems (unrelated Rheumatoid Arthritis) or socio-professional.

Design outcomes

Primary

Measure	Time frame
plasma concentration of C-reactive protein	48 hours after the end of the exercise

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026