Acceptability of HIV Oral PrEP Among MSM and TGW

Acceptability of HIV Oral Pre-Exposure Prophylaxis (PrEP) Among Men Have Sex With Men (MSM) and Transgender Women (TGW)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02855606

Enrollment

105

Registered

2016-08-04

Start date

2015-12-31

Completion date

2019-05-30

Last updated

2022-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patient Acceptance of Health Care

Keywords

Oral PrEP, TGW, Thai MSM

Brief summary

The purpose of this study is to determine the factors associated with acceptability to oral HIV pre-exposure prophylaxis (PrEP) among Thai men who have sex with men (MSM) and transgender women (TGW).

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

MALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* MSM or TGW at age18 years or older at enrollment * Able to read and write effectively in Thai language * Negative HIV testing (by assigned rapid tests) at enrollment * Available to return for the study visits and willing to comply with study requirements * Willing to provide reachable contact numbers and address * Creatinine clearance ≥ 60 mL/min * Negative urine protein * Negative HBs Ag

Exclusion criteria

* Symptoms suggestive for acute HIV seroconversion * Participating in any interventional HIV research * Has any physical or mental condition(s) that, in the opinion of the investigator(s), complicate interpretation of study outcome data

Design outcomes

Primary

Measure	Time frame	Description
Acceptability and factors affecting the decision to take oral PrEP	1 year	After receiving information about PrEP, the participants will have a chance to decide whether they want to take PrEP or not. The set of questions asking about reason(s) for taking (or not taking) PrEP are used to evaluated the acceptability. The questions will evaluate multiple aspects such as knowledge about PrEP (efficacy and medications side effect), personal belief about PrEP, sexual practice, social stigmata, and concern for HIV resistance. The participants will answer these questions via Computer-Assisted Self Interviewing (CASI).

Secondary

Measure	Time frame	Description
Adherence to PrEP by self-report	1 year	Among the participants who decide to take PrEP, the adherence will be evaluate by self-report (directly to medical staff and via Computer-Assisted Self Interviewing).
Adherence to PrEP by pill count	1 year	Among the participants who decide to take PrEP, the adherence will be evaluate by pill count.

Countries

Thailand

Outcome results