Cardiomyopathy, Myocarditis, Ischemic Heart Disease
Conditions
Keywords
myocardial tissue characterization
Brief summary
The overall goal of this project is to evaluate the clinical potential of fast quantitative myocardial tissue characterization using recently emerged Cardiac Magnetic Resonance Imaging (CMR) techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases, such as ischemic heart disease, cardiomyopathies, and myocarditis.
Interventions
OTHERCardiac Magnetic Resonance (CMR) imaging techniques
Evaluation of clinical potential of fast quantitative myocardial tissue characterization using recently emerged CMRI techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases.
Sponsors
Medical University of South Carolina
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* Subject must be 18-90 years of age. * Subject must be previously diagnosed with or suspected to have one of the following conditions. * Myocardial ischemia or infarction (group 1) * Hypertrophic cardiomyopathy (group 2) * Infiltrative cardiomyopathy (group 3) * Myocarditis (group 4) * Subject must have been referred for a clinically indicated CMR.
Exclusion criteria
* Subject has any implanted device or condition in which an MR scan would be contraindicated. * Subject has an acute psychiatric disorder or is cognitively impaired. * Subject is using or is dependent on substances of abuse. * Subject is unwilling to comply with the requirements of the protocol. * Subject has previously entered this study. * Subject has an allergy against MRI contrast agents. * Subject is in acute unstable condition.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical value of fast T1, T2, and T2* mapping of the left ventricle for the assessment of necrosis/scar, edema, and possible intramyocardial hemorrhage in patients with heart disease. | 2 years |
Countries
United States
Contacts
Primary ContactMark Ghent, BA
Backup ContactJacob Rowe, BA
Outcome results
None listed