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Study of the Anti-tumoral Immune Response

Study of the Anti-tumoral Immune Response T Cells Cluster of Differentiation 4 (TCD4): Proof of the Concept in Breast Cancer and Glioma

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02854644
Acronym
ERISA
Enrollment
167
Registered
2016-08-03
Start date
2014-01-27
Completion date
2021-10-27
Last updated
2022-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer, Glioma

Brief summary

This study evaluates the frequency of the spontaneous T cells specific CD4 answers of tumoral antigens breast cancer and glioma.

Interventions

Sponsors

Centre Hospitalier Universitaire de Besancon
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Performance status 0,1 or 2 * breast cancer or glioma * Arm glioma: patients without anti-tumoral treatment * Arm breast cancer: inclusion before treatment * Arm breast cancer HER2: patients with current therapy

Exclusion criteria

* Psychiatric disease compromising the understanding of the information or the realization of the study * vulnerable People according to the law (minors, adults under protection, private persons of freedom ...) * Unaffiliated People to the Social Security * People being for the period of exclusion from another study * Life expectancy estimated unless 3 months. * For patients in Arm glioma: patients having already begun a systematic treatment. * For patients with a breast cancer: patient already under current therapy

Design outcomes

Primary

MeasureTime frame
Spontaneous immune responses of T cells CD4 specific tumor antigens15 months

Secondary

MeasureTime frame
T cells level15 months

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026