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Probabilistic Risk Modeling for Disorder Post Traumatic Stress (PTSD) After the Attacks in Paris In November 2015

Definition of a Probabilistic Model of the Evolution of an Acute Stress Disorder (ASD ) to a Posttraumatic Stress Disorder (PTSD): an Analytical Prospective Cohort Study of Patients Directly Involved in Attacks Terrorists of 13 November 2015

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02853513
Acronym
BV13
Enrollment
100
Registered
2016-08-03
Start date
2016-07-31
Completion date
2018-07-31
Last updated
2017-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stress Disorders, Post-Traumatic

Brief summary

The scientific approach of this project proposes to build a cohort of psychological injuries post-attack of 13 November 2015. This is called patients involved, ie patients who directly witnessed the events and having the most either came under automatic gunfire or were close to an explosion, whether or not physically injured. The main objective is to define and validate a model of transition from acute stress disorder (ASD) to posttraumatic stress disorder (PTSD) for better detection of the risk of unfavorable and thus better patient supported. The first step is to determine independent risk factors found in analytic prospective cohort study. Bayesian models are well suited to exercise because they can integrate (i) the context related to the patient, (ii) the context related to the trauma itself, and (iii) the immediate reactions and long-term to the latter . They are particularly suited to understanding the brain disordered by saying down information (prior probability) wrong by improper memory of the traumatic event. The confrontation of these descending information and perceived bottom-information could be partly responsible for the symptoms of PTSD. Once validated, the model will characterize the individual level the most at risk of unfavorable patients (calculating a probability of developing PTSD) and to assess the epidemiological impact on long-term cohort of event considered. These determinations are necessary prerequisites to optimize the means of support for these current and future casualties. The investigators main objective is to define a Bayesian model describing a resilient functioning facing a trauma which also allows to describe a possible evolution of the ASD to PTSD by an error. The state of PTSD or not will be determined by the PCL-S scale.

Detailed description

cohort tracking study

Interventions

None listed

Sponsors

Assistance Publique - Hôpitaux de Paris
CollaboratorOTHER
University of Lorraine
CollaboratorOTHER
University Hospital, Tours
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* patients who directly witnessed the events and having the most either came under automatic gunfire or were close to an explosion, whether or not physically injured

Exclusion criteria

* persons not physically present on the premises at the time of the attacks. * Inability to understand or read French. * Persons unable to express personal consent under whose major legal or private protection of liberty by judicial or administrative decision , or hospital emergency or without their consent

Design outcomes

Primary

MeasureTime frameDescription
Post traumatic disorder check list6 months after traumaPTSD diagnose

Secondary

MeasureTime frameDescription
Hamilton depression scale6 months after traumapersonality

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026