Circadian Rhythm and Attack-timing in Episodic Cluster Headache Patients in- and Outside of Bout: an Actigraphic Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02853487

Enrollment

Registered

2016-08-03

Start date

2016-07-31

Completion date

2018-02-01

Last updated

2018-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cluster Headache

Keywords

Cluster headache, actigraphy, circadian rhythm

Brief summary

The aim is to investigate circadian rhythm in episodic cluster headache using actigraphy.

Detailed description

The aim is to investigate circadian rhythm in episodic cluster headache patients in- and outside of bout. This will be done using actigraphy and a short diary for 2 weeks in each period. A secondary outcome is to look at attack occurence and physical activity before and during an attack.

Interventions

DEVICEActigraphy

An actigraph from Philips

OTHERDiary

Questions on sleep times and awakenings and attacks in the morning and evening for 2 weeks.

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

PATIENTS Inclusion Criteria: * Age between 18 and 65 years of age * Episodic cluster headache * The patient can differentiate cluster headache from other primary headaches if he suffers from any.

Exclusion criteria

* Circumstances, determined by the PI, that makes the patient ineligible. * Changes in preventive medication within 7 days before the study initiation and during the 2 weeks. * Changes in antidepressive medication or antipsychotic medication within 2 weeks before the study initiation and during the 2 weeks. * Serious somatic and/or psychiatric disorders * Alcohol intake \> 50 units pr.week * Pregnancy / breastfeeding * Patient cannot accept the conditions of the trial * Patient does not understand Danish. CONTROLS Inclusion Criteria: \- Age between 18 and 65 years of age

Design outcomes

Primary

Measure	Time frame	Description
Circadian rhythm	Circadian rhythm is assessed after 2 weeks	After 2 weeks of actigraphy, the circadian rhythm will be assessed using Philips Actiware 6 program.

Secondary

Measure	Time frame
Attack occurence	The time of day will be assessed after 2 weeks
Physical activity before and during an attack	Increase / decrease in activity count will be described after 2 weeks.

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 23, 2026