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Trajectories of Psychopathology in Response to NET

Progression and Remittance of Traumatic Stress-related Symptoms During and After Narrative Exposure Therapy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02852616
Acronym
TOP-NET
Enrollment
85
Registered
2016-08-02
Start date
2015-12-31
Completion date
2018-08-31
Last updated
2019-10-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Posttraumatic Stress Disorder (PTSD)

Keywords

Course, Posttraumatic Stress Disorder, Narrative Exposure Therapy

Brief summary

Narrative Exposure Therapy (NET) has been proven to be effective in the treatment of Posttraumatic Stress Disorder (PTSD) and trauma-related depression in more than a dozen controlled clinical trials. Symptom reduction was greatest during long-term follow-ups after the completion of the therapy. In the current study, we will investigate the progression of PTSD symptoms and emotional stress before, during and after therapy. After a semi-structured interview all participants will be asked to report in monthly telephone interviews their core symptoms. Structured interviews after 6 and 12 months are used to validate the outcome. A convenience sample of individuals with a PTSD will be offered participation in the study.

Detailed description

Participants will be recruited through the Center of Excellence for Psychotraumatology, University of Konstanz, with focus on refugees. All of them (approx. 100) will receive a structured interview and a detailed diagnosis. The interview includes questions about sociodemography, traumatic events, PTSD and depression symptomatology. Individuals with a PTSD diagnosis (up to 30) will be offered a Narrative Exposure Therapy (NET). Irrespective of treatment and diagnosis, respondents are asked to participate in monthly telephone interviews assessing trauma-related and emotional distress and changes in life. Interviews assessing PTSD, depression symptoms and emotional distress will be conducted 6 and 12 months after the initial interview. In addition, participants receiving NET will rate their PTSD symptoms and functionality prior to each therapy session.

Interventions

BEHAVIORALNarrative Exposure Therapy

8 - 15 sessions: 1 lifeline session, 5 - 12 sessions narrative exposure, 1-2 sessions of future-oriented counselling

Sponsors

University of Konstanz
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
12 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* For treatment group: PTSD diagnosis (DSM-IV or V) * For non-treatment group: none

Exclusion criteria

* Acute psychosis * Cerebro-organic disease * Acute drug or alcohol intoxication * Already receiving another psychotherapy * Anti-epileptic drugs at baseline

Design outcomes

Primary

MeasureTime frameDescription
Change in the progression of PTSD symptoms (PCL-5)baseline, 3 and 6 months follow-upPTSD symptoms are measured with the PTSD Checklist - 5 (PCL-5; Weathers, Litz, et al., 2013)

Secondary

MeasureTime frameDescription
Change in the progression of emotional distress symptoms (RHS-15)up to 1 yearEmotional distress symptoms are measured with the Refugee Health Screener - 15 (RHS-15; Hollifield, et al., 2013)

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 27, 2026