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Prevalence and Risk Factors of Reventilation Syndrome in a Population of Patients Under Ventilation for Whatever Reason

Prevalence and Risk Factors of Dreentilation Syndrome in a Population of Patients Under Ventilation for Whatever Reason

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02851446
Acronym
DEVENTILATION
Enrollment
300
Registered
2016-08-01
Start date
2015-10-31
Completion date
Unknown
Last updated
2016-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevalence of and Factors Associated With Reventilation Syndrome (DS)

Brief summary

Non-invasive nocturnal ventilation is an effective treatment for chronic respiratory failure, whether due to obstructive (COPD), restrictive or neuromuscular causes, notably for patients in the last two categories for whom it significantly prolongs life expectancy. Overall, the treatment is well tolerated, its principal adverse effects being discomfort related to the mask. In certain patients, morning dyspnoea when the mask is removed has been described. This is disabling as it limits everyday activities for at least 30 minutes, and defines deventilation syndrome. The pathophysiology of this syndrome is uncertain, notably the roles of hyperinflation, patient/ventilator asynchrony, or the sudden increase in diaphragmatic work after a night of rest. The aim of this study is to investigate the prevalence of and factors associated with reventilation syndrome (DS) in a population of patients with ventilation whatever the reason, in a stable state, and followed by the medical devices department of Dijon CHU, so as to better understand the mechanisms. Patients with DS will subsequently be invited to participate in a therapeutic trial.

Interventions

OTHERmeasure dyspnoea> Borg 7

Sponsors

Centre Hospitalier Universitaire Dijon
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patients over 18 years old * ventilation for whatever reason * in the ST mode * not in life support * at more than 1 month after the last episode of respiratory decompensation

Exclusion criteria

* guardianship * inability to understand instructions and provide consent * uncontrolled psychiatric disease

Design outcomes

Primary

MeasureTime frame
presence of diagnostic criteria for reventilation Syndrome (dyspnoea > Borg 7)at withdrawal of the machine, disabling for everyday activities for at least 30 minutes after stopping the ventilation

Countries

France

Contacts

Primary ContactClément FOIGNOT
clement.foignot@chu-dijon.fr03.80.29.37.72

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026