Skip to content

Brain Volumes of Very Low Birth Weight Infants Measured by Cranial Ultrasonography

Neonatal Cranial Ultrasonography for Measuring Brain Volumes of Very Low Birth Weight Infants

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02848755
Enrollment
341
Registered
2016-07-28
Start date
2017-01-01
Completion date
2018-06-09
Last updated
2018-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infant, Premature

Brief summary

Neonatal cranial ultrasound (US) remains the method of choice to detect brain injury in high risk preterm infants on neonatal intensive care units (NICU). It is a non-invasive, inexpensive bedside tool and examinations can be repeated as often as necessary without major disturbance of vulnerable infants. The anterior and posterior fontanelles from excellent acoustic windows to examine the deep midline and periventricular regions of the brain.Some data demonstrated that cerebral palsy can be accurately predicted with US. However, cranial US is not very suitable for investigating cortical regions or structures in the posterior fossa. There is limited data for very preterm infants.The investigators aimed to measure ventricular index, cranial height, biparietal diameter and calculate brain volume in a huge number of infants.

Interventions

DEVICECranial ultrasonography

Sponsors

Netherlands: Ministry of Health, Welfare and Sports
CollaboratorOTHER_GOV
Zekai Tahir Burak Women's Health Research and Education Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
1 Days to 40 Weeks
Healthy volunteers
No

Inclusion criteria

* both gender * \<1500 gr \<32 week- * 1-28 days neonates

Exclusion criteria

* Anomalies and no viability

Design outcomes

Primary

MeasureTime frameDescription
measurements of ventricular indexes of preterm infants12 monthsmeasuring distance with 2D USG
measurements of brain volumes of preterm infants12 monthssubtracting the ventricular volumes from the total brain volume measured with 2D

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 1, 2026