Anemia, Iron-Deficiency, Deficiency, Vitamin A
Conditions
Keywords
Fortified-blended foods, Extrusion, Sorghum, Cowpea, Vitamin A, Iron, Protein, Food Aid, Anemia, Iron-Deficiency, Deficiency, Vitamin A, Growth Velocity, Stunting, Wasting, Protein-Energy Malnutrition, Complementary Feeding, Corn, Soy, Fortified Foods, Food assistance
Brief summary
Corn-soy vitamin and mineral fortified blended foods (FBFs) are primarily used for food aid, although sorghum and cowpea may be suitable alternative FBF commodities. The objective of the Micronutrient Fortified Food Aid Pilot Project (MFFAPP) Tanzania Efficacy Study is to determine whether newly formulated, extruded sorghum- and cowpea-based FBFs have equal, or better, nutritive value and acceptance compared to a traditional corn-soy blend. The effectiveness of each blend will be determined in an efficacy study of Tanzanian children under the age of 5 that are deficient, or at risk for deficiency, in iron and vitamin A.
Interventions
OTHERCorn Soy Blend Plus (CSB+)
OTHERCorn Soy Blend 14 (CSB14)
OTHERWhite Sorghum Cowpea Blend Variety 1
OTHERWhite Sorghum Cowpea Blend Variety 2
OTHERRed Sorghum Cowpea Blend
OTHERWhite Sorghum Soy Blend
Sponsors
Project Concern International - Tanzania
National Institute for Medical Research, Tanzania
United States Department of Agriculture Foreign Agricultural Service
Kansas State University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
6 Months to 53 Months
Healthy volunteers
No
Inclusion criteria
* Hemoglobin \<10.3mg/dl * Weight-for-height z-scores \>-3
Exclusion criteria
* Exclusive breastfeeding * Unwillingness to travel to health facilities * Enrollment of child in school during study period * Anticipated relocation of the family during the study * Allergy to the fortified-blended food product ingredients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hemoglobin Change | 0, 10, 20 weeks (baseline, midline, and end line) | — |
| Dried blood spot retinol binding protein change | 0, 10, 20 weeks (baseline, midline, and end line) | Assessment of vitamin A status |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Weight-for-height change | 0, 10, 20 weeks (baseline, midline, and end line) | — |
| Weight-for-age change | 0, 10, 20 weeks (baseline, midline, and end line) | — |
| Mid-upper arm circumference change | 0, 10, 20 weeks (baseline, midline, and end line) | — |
| Moderate malnutrition status change | 0, 10, 20 weeks (baseline, midline, and end line) | Weight-for-age between -3 and -2 z-scores below the median of the WHO child growth standards |
| Height-for-age change | 0, 10, 20 weeks (baseline, midline, and end line) | — |
Outcome results
None listed