Pain
Conditions
Keywords
Postcesarean Section, Postoperative
Brief summary
This present investigation aims to determine whether a transversus abdominous plane(TAP) block, utilizing liposomal bupivacaine (Exparel), at the conclusion of a cesarean section decreases post-operative pain. The hypothesis is that performance of the TAP block with liposomal bupivacaine will decrease post-operative narcotic use.
Interventions
DRUGTAP block w Liposomal bupivacaine
TAP block w Liposomal bupivacaine diluted to 0.66% (20 mLs)
PROCEDURETAP block w normal saline
TAP block w normal saline -preservative free 0.9% sodium chloride (20mLs)
Sponsors
Milton S. Hershey Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients \>18 years of age * Scheduled cesarean section with or without bilateral tubal ligation * Planned performance of a Pfannenstiel incision * Patients are schedule to have a cesarean section with a member of the Women's Health or Maternal and Fetal Medicine Departments at Penn State University Hershey S. Medical Center
Exclusion criteria
* History of opioid use * History of chronic pain syndrome * Use of general anesthesia during cesarean delivery * Postoperative SICU admission * Postpartum hemorrhage (defined as an Estimated Blood Loss of greater then 1,000mL upon completion of the cesarean section)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative narcotic use | initial 48 hours postoperatively | Patient use of standard postoperative narcotics (percocet) will be measured. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Subjective pain scores using 1-10 VAS system | initial 48 hours postoperatively | Subjective pain scores using 1-10 VAS system will be measured |
Countries
United States
Outcome results
None listed