Coronary Artery Disease
Conditions
Keywords
intravascular ultrasonography, Computed Tomography
Brief summary
The aims of this study are 1) to identify IVUS determinants of the CAMS-derived myocardial territories subtended to the diseased vessels, 2) to find IVUS determinant for the extent of CAMS-derived myocardial size, and 3) to develop the mathematical model that integrates the IVUS information about myocardial territory and stenosis severity and predicts the extent of CAMS-derived myocardial size.
Interventions
OTHERIntravascular Ultrasound, coronary computed tomography angiography
Sponsors
Boston Scientific Corporation
Asan Medical Center
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age 20years or older * Patients who have at least one epicardial coronary artery lesion (including isolated left main disease or side branch) with visually estimated diameter stenosis \>50% and take coronary angiography, CT angiography and IVUS * Willing and able to provide informed written consent
Exclusion criteria
* In-stent restenosis * Bypass graft * Suspected coronary spasm even after sufficient nitrate injected * Cases in which the IVUS imaging catheter failed to cross the lesion * Poor quality IVUS or CT images * Visible collateral flow on angiography
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mathematically-predicted ischemic size (by using IVUS parameters) vs. CAMS-derived myocardial size subtended to the stenotic segment | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| Impact of plaque characteristics (attenuated plaque, plaque rupture, calcification, thrombosis, etc.) assessed by IVUS on the ischemic burden assessed by CAMS | 1 year |
| Incidence of MACE comprising death, nonfatal myocardial infarction or target vessel revascularization | 1 year |
Countries
South Korea
Outcome results
None listed