Brain Tumor
Conditions
Brief summary
It is still challenging to assess intravascular volume status in spontaneously breathing patients. Recently, the measurement of corrected flow time in carotid artery was introduced as quite useful, simple and noninvasive for the evaluation of circulating blood volume change. The aim of this study is to evaluate whether corrected carotid artery flow time as determined by ultrasonography can be a predictor of fluid responsiveness in spontaneously breathing patients before induction of general anesthesia.
Interventions
Corrected carotid artery flow time is measured using 10-5 MHz linear probe on a portable ultrasound machine. On the two-dimensional image, the optimal image of the long-axis view is obtained at the left common carotid artery. The sample volume is placed on the center of the lumen, 2 cm proximal to the bulb, and a pulsed wave Doppler examination was performed while the Doppler beams were adjusted to ensure \< 60° of angle for the best signal. Then, cardiac cycle time and carotid flow time is measured. Carotid flow time is measured between the upstroke of the flow tracing and the dicrotic notch, and it is corrected for pulse rate by dividing flow time by the square root of the cardiac cycle time to calculate corrected carotid artery flow time (flow time/√cycle time).
Sponsors
Study design
Eligibility
Inclusion criteria
* adult patients (19-80 years of age) who were scheduled to undergo elective neurosurgery for brain tumor
Exclusion criteria
* BMI \> 35 or \< 15 kg/m2 * the presence of carotid artery stenosis \> 50% * systolic blood pressure \> 160 mmHg * cardiac rhythm other than sinus * intracardiac shunt 6. valvular heart disease * a left ventricular ejection fraction of \< 50% * right ventricular dysfunction 9 * chronic obstructive pulmonary disease * pulmonary hypertension * chronic kidney disease (eGFR \< 60 mL/min/1.73m2) * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| ultrasonographic measurement of corrected flow time in carotid artery | right before fluid loading | The ultrasonographic measurement of corrected flow time in carotid artery will be performed before fluid loading. |
Countries
South Korea