Laparoscopic Renal Surgery, Nerve Block, Pain Management
Conditions
Brief summary
This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay and incidence of chronic pain,et al. between single-injection QLB(quadratus lumborum block)+ intravenous patient-controlled analgesia (IPCA) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing laparoscopic renal surgeries.
Interventions
Inject local anesthetics in between quadratus lumborum and psoas major without continuous local infusion
The curved (C1-5) probe of Philip CX 50 Ultrasound Scanner is used for scan
DEVICEPAJUNK StimuLong
* 0.6ml/kg 0.5% ropivacaine with 1:200,000 adrenaline. * given immediately after the correct position of the tip of the needle has been verified.
bolus: 1.5\ 2mg, lock time: 10min, 1h limitation: 6\ 8mg
Sponsors
Cui Xulei
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
17 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Age 18-70 yrs * American Society of Anesthesiologists physical statusⅠ-Ⅲ * Undergo laparoscopic nephrectomy * Informed consent
Exclusion criteria
* A known allergy to the drugs being used * Coagulopathy, on anticoagulants * Analgesics intake, history of substance abuse * Participating in the investigation of another experimental agent * Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cumulative morphine consumption | within 48 postoperative hours |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| nausea and vomiting score | within 24 hours after the surgery | — |
| pruritus score | within 24hour after the surgery | — |
| ambulation time | within the 7 days after surgery | — |
| The pain scores determined by the numeric rating scale (NRS, 0-10) | At 0, 2,4, 8, 12, 24 ,48,72hours after the surgery | — |
| quality of recovery | 3days and 5days after surgery | use the self-assessment 15 item QoR scale to assess the patient's recovery |
| Postoperative hospital length of stay | Up to 6 weeks | — |
| patient satisfaction with anesthesia | 48 hours after surgery | use the Chinese version Bauer questionnaire to assess the patient satisfaction with anesthesia |
| time of recovery of bowl movement | within the 5 days after surgery | — |
Countries
China
Outcome results
None listed