Patients ASA I, II, III
Conditions
Keywords
physical status I-III;, age > 55 yr), undergoing surgery (duration, > 1 h)
Brief summary
Background: Postoperative cognitive dysfunction (POCD) in elderly patients after noncardiac surgery is a common problem. Therefore,this study was designed to assess POCD after closed-loop coadministration of propofol and remifentanil guided by bispectral index in comparison to intravenous anesthesia in elderly patients undergoing major noncardiac surgery. Methods: After approval of the local ethical committee was obtained, 204 patients (American Society of Anesthesiologists physical status I-III; age, \> 55 yr) undergoing surgery (duration, \> 1 h) were enrolled into this pospective randomized monocenter study. Patients received anesthesia 3 days after using a neuropsychological test battery.
Interventions
PROCEDUREneuropsychological test battery
Sponsors
Centre Hospitalier Universitaire de Besancon
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
55 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* American Society of Anesthesiologists physical status I-III; * undergoing surgery (duration, \> 1 h)
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of early POCD in elderly patients (aged 55 yrs or older) | 3 DAYS |
Countries
France
Contacts
Primary ContactE SAMAIN, PR
Backup ContactLucie VETTORETTI
Outcome results
None listed