Neonatal Resuscitation
Conditions
Keywords
resource limited setting, Thailand-Myanmar border
Brief summary
The primary objective of this study is to describe mortality of newborns who received basic, advanced or no neonatal resuscitation immediately after birth at Shoklo Malaria Research Unit.
Detailed description
This is a retrospective, descriptive study of hospital records will be conducted. The existing dataset of newborns of ≥28 weeks gestation delivered at Shoklo Malaria Research Unit clinics from January 2008 to December 2015 will be analysed. In the dataset, 15224 newborns fulfill the inclusion criteria and therefore they will all be analysed with IBM SPSS Statistics 22 for Windows. Descriptive statistics will be used to define: a) the proportion of newborns alive at 24 hours, 7 days, 28 days, and at 1 year, following resuscitation at SMRU birthing rooms and b) the number of newborns requiring basic and advanced resuscitation. Measurements of correlation coefficient will be used to compare Shoklo Developmental test scores and developmental milestones attained at 1 year in resuscitated and non-resuscitated infants. The Pearson correlation coefficient will be used if the relationship between two variables is found to be linear. Antenatal, perinatal and postnatal characteristics associated with neonatal resuscitation will be defined by logistic regression analysis.
Interventions
None listed
Sponsors
University of Oxford
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 28 Weeks
Healthy volunteers
Yes
Inclusion criteria
* Liveborn singletons birthed at SMRU * ≥28 weeks gestation
Exclusion criteria
* Stillborn infants * Liveborn infants birthed at home or in the Thai hospital * Major congenital abnormalities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality 24 hours after birth of babies who received basic resuscitation | 24 hours |
| Mortality 24 hours after birth of babies who received advanced resuscitation | 24 hours |
| Mortality 24 hours after birth of babies who did not receive neonatal resuscitation | 24 hours |
Secondary
| Measure | Time frame |
|---|---|
| Mortality at one year | 1 year |
| Proportion of live births requiring basic or advanced neonatal resuscitation. | 24 hours |
| Number of newborns who received basic resuscitation, as a proportion of all live births. | 24 hours |
| Number of newborns who received advance resuscitation, as a proportion of all live births. | 24 hours |
| characteristics of antenatal infant receiving neonatal resuscitation compared to non-resuscitated infants as assessed by physiological parameter | 24 hours |
| Month of achieved milestones (crawl, walk, talk) in in infants who received basic or advanced neonatal resuscitation or no resuscitation. | up to 1 year of age |
| characteristics of perinatal infants receiving neonatal resuscitation compared to non-resuscitated infants as assessed by physiological parameter | 24 hours |
| characteristics of neonatal infants receiving neonatal resuscitation compared to non-resuscitated infants as assessed by physiological parameter | 24 hours |
| Shoklo Developmental test scores at 1 year in infants who received basic or advanced neonatal resuscitation or no resuscitation. | up to 1 year of age |
| Mortality at 7 days | 7 days |
| Mortality at 28 days | 28 days |
Countries
Thailand
Outcome results
None listed