Cortical Activation in Individuals With Finger Amputation During Mirror Versus Imagery Treatment

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02838485

Enrollment

Registered

2016-07-20

Start date

2016-08-31

Completion date

Unknown

Last updated

2016-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amputees

Brief summary

Goals : ( a) to examine differences in cortical activity during hand movements with a mirror compared to imagery of the same movements, and (b) to examine correlation between cortical activity during imagery or mirror treatment and the pain and performance measures in finger amputees. A cross-sectional study of 20 subjects in a Functional Magnetic Resonance Imaging (fMRI) preforming mirror therapy hand movement and imagery hand movement. Also, Visual Analogue Scale for pain and the Disability of the Arm, Shoulder and Hand (DASH) questionnaire and Jebsen Taylor Hand Function Test will be used.

Detailed description

Goals : ( a) to examine differences in cortical activity during hand movements with a mirror compared to imagery of the same movements, and (b) to examine correlation between cortical activity during imagery or mirror treatment and the pain and performance measures in finger amputees. A cross-sectional one-meeting study of 20 subjects (finger amputees) in a Functional Magnetic Resonance Imaging (fMRI) preforming mirror therapy hand movement and imagery hand movement. Also, Visual Analogue Scale for pain and the Disability of the Arm, Shoulder and Hand (DASH) questionnaire and Jebsen Taylor Hand Function Test will be used.

Interventions

OTHERMirror

The healthy hand will be mirrored and the amputated hand unseen by the subject while performing hand movements.

OTHERImagery

The subject will be asked to imagine performing hand movements.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 67 Years

Healthy volunteers

Inclusion criteria

* Following unilateral traumatic finger or fingers amputation (1 to 3 fingers) * Self-reported limited functionality, sensory disorder or pain

Exclusion criteria

* Are not comparable with MRI restrictions * Chronic pain disease * Psychiatric condition

Design outcomes

Primary

Measure	Time frame	Description
Cortical activity	1 hour	Activation of supplementary motor area (SMA), S1 and M1.

Secondary

Measure	Time frame	Description
Visual analogue scale	10 minutes	Filled by the subject for subjective pain in residuum discomfort.
Disability of the Arm, Shoulder and Hand	30 minutes	Questionnaire regarding the disability and daily activities difficulties.
The Jebsen Taylor Hand Function Test	30 minutes	Standard evaluation of hands functionality.

Countries

Israel

Contacts

Primary ContactIsabella Schwartz, MD

isabellas@hadassah.org.il

Backup ContactHadas Lemberg, PhD

lhadas@hadassah.org.il00 972 2 6777572

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026