Adverse Drug Reaction
Conditions
Keywords
adverse drug reaction, hospital mortality, incidence
Brief summary
The purpose of this study is to determine the incidence of drug-related deaths in a university hospital during the year 2015
Detailed description
The investigators aimed to determine the incidence of drug-related mortality of admitted patients in a university hospital during the year 2015
Interventions
DRUGadverse drug reaction
drug-related death
Sponsors
Germans Trias i Pujol Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* inpatients deaths and drug-related deaths.
Exclusion criteria
* death patients in the emergency room, patients with a death diagnosis not available, and dead patients due to other causes non-drug related.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of drug-related deaths of all hospital admissions | during the year 2015 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of drug-related deaths with drug interactions between suspected drugs | during the year 2015 | — |
| Number of preventable drug-related deaths assessed by Schumock criteria | during the year 2015 | — |
| Number of drug-related deaths with polypharmacy | during the year 2015 | Polypharmacy: when patient received \>10 drugs |
| Number of drug-related deaths with autopsy | during the year 2015 | — |
| Number of drug-related deaths with the suspected drug started the previous week | during the year 2015 | — |
| Number of drug-related deaths with certain or probable categories assessed by World Health Organization (WHO) criteria and Naranjo algorithm | during the year 2015 | — |
| Number of drug-related deaths presented during hospitalization | during the year 2015 | — |
| Risk factors of drug-related deaths | during the year 2015 | risk factors assessed: age, sex, Charlson score, and hospitalization length |
| Incidence of drug-related deaths of all inpatients deaths | during the year 2015. | — |
| Number of drug-related deaths in which the suspected drug had a contributive role | during the year 2015 | — |
Outcome results
None listed