Breath Volatile Organic Compounds Patterns of Lung Transplant Patients With Chronic Lung Allograft Dysfunction

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02836938

Enrollment

Registered

2016-07-19

Start date

2016-06-30

Completion date

2016-12-31

Last updated

2017-02-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Lung Allograft Dysfunction (CLAD)

Brief summary

It's the aim of this study to clarify, whether the non-invasive assessment of breath can serve as a novel clinical tool to assist in the diagnosis of CLAD. If different stages of BOS can be discriminated by the level of certain VOCs than there would also be a potential to actually predict the development at an early stage and would enable an earlier intervention.

Interventions

OTHERCollection of exhaled breath volatile organic compounds

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Outpatient bilateral lung transplant recipients including combined transplants

Exclusion criteria

* Active Smoking Oxygen therapy Infection with multi or pan-resistant bacteria

Design outcomes

Primary

Measure	Time frame
Concentration of exhaled breath volatile organic compounds	one sample will be collected between 6 month and 20 years after lung transplantation

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026