Influence of Perception of Patients Suffering of Knee Osteoarthritis Regarding Effectiveness of Intra-articular Injection

Influence of Perception of Patients Suffering of Osteoarthritis of Knee Over the Effectiveness and Tolerance in Intra-articular Injection of Corticoids: a Prospective, Controlled and Randomized Study

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02835521

Enrollment

100

Registered

2016-07-18

Start date

2016-08-31

Completion date

2017-07-31

Last updated

2016-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Brief summary

Introduction; reception must be understood as the offered attention within the relationship between a healthcare worker and the patient, including attitudes of inclusion, hearing, valorization of complains and identification of needs, being these individual collective. As a part of this process, communication is a primary and indispensable toll through which the healthcare team and the patient interchange information. Objective: to evaluate the influence of perception of patients suffering of knee osteoarthritis over fear, catastrophizing of pain and effectiveness, related to intra-articular injection od corticosteroids. Material and method: it will be performed a prospective, controlled and randomized study eith a blind evaluator on patients with symptomatic knee osteoarthritis submitted to joint injection. A hundred patients suffering of symptomatic knee osteoarthritis coming from the outpatient area of Rheumatology Division of Federal University of Sao Paulo (UNIFESP) will be evaluated, 50 belonging to the intervention group (reception) and 50 to a control group.

Interventions

PROCEDUREReception

DRUGJoint injection with triamcinolone hexacetonide

joint injection with corticosteroids

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

ALL

Age

50 Years to 85 Years

Healthy volunteers

Inclusion criteria

* knee osteoarthritis according to american college of rheumatology criteria * no previous experience of joint injection * stable use of drugs for osteoarthritis treatment for at least 3 months * stable dose of corticosteroids, non hormonal anti-inflammatory and analgesics in the previous month * pain on knee between 3 and 7 in the visual analogue scale * signe the informed consent term * radiologic classification between 1-3 (kellgren and Lawrence classification)

Exclusion criteria

* joint disease of different etiology * coagulation alteration * non treated fibromyalgia * litigation * diabetes mellitus and systemic arterial hypertension out of control * allergy of lidocaine or triamcinolone hexacetonide

Design outcomes

Primary

Measure	Time frame	Description
Change on pain	baseline, after 1, 4 and 12 weeks	Pain will be evaluated with an visual analogue scale

Secondary

Measure	Time frame	Description
Change on functional capacity	baseline, after 1, 4 and 12 weeks	functional capacity will be evaluated with Health assesment questionary (HAQ)
Change on Catastrophizing	baseline, after 1, 4 and 12 weeks	Catastrophizing will be evaluated with an Catastrophizing test

Contacts

Primary ContactSandra R Toffolo, Msc nurse

s-regina-toffolo@bol.com.br551155764239

Backup ContactRita NV Furtado, PhD MD

rvfurtado@hotmail.com551155764239

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026