Novel Coating to Minimize Bacterial Adhesions and Tooth Wear in Denture Acrylic

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02834832

Enrollment

Registered

2016-07-15

Start date

2016-11-30

Completion date

2019-07-18

Last updated

2020-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Denture Stomatitis, Wear of Denture Teeth

Brief summary

This study evaluates the effect of coatings on bacterial adhesion on denture acrylic and the wear of denture teeth.

Detailed description

Denture stomatitis is a prevalent disease among removable denture wearers. The cause of this disease stems from a myriad of factors including host immunity and poor oral hygiene. Denture acrylic material is very conducive for the growth and adhesion of bacteria because of its porous nature. The application of plasma enhanced chemical vapor deposited (PECVD) coatings on the surface of acrylic dentures can produce a less porous surface which may minimize the adhesion of bacteria and therefore colonization. The goal is the application of these coatings will help minimize the occurrence of denture stomatitis. Another issue of removable dentures is the low wear resistance of denture teeth. The application of these coatings on denture teeth should minimize wear of these teeth and prolong the life of removable dentures.

Interventions

DEVICEPECVD coating

SiO2/SiC coatings will be applied to the surface of removable partial dentures and denture teeth.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

21 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients who are missing some teeth and will need removable dentures

Exclusion criteria

* Medical contraindication for dental treatment

Design outcomes

Primary

Measure	Time frame	Description
Change in Bacterial Count	2,4 and 12 weeks	Biofilms on the tissue surface of the dentures will be obtained for the aforementioned time intervals. Biofilm counts will be analyzed to determine the effect of the coatings on the number of disease causing bacteria on the surface of the denture

Secondary

Measure	Time frame	Description
wear of denture teeth	6 months	Denture teeth will be analyzed for wear at 6 months to determine the effect of PECVD coatings on the wear of denture teeth.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026