Acute Respiratory Failure, Pneumonia
Conditions
Keywords
high flow nasal cannula, success, failure, ROX index
Brief summary
The purpose of the study was to describe early predictors and to develop a prediction tool that accurately identifies the need for mechanical ventilation in pneumonia patients with acute respiratory failure treated with High Flow nasal cannula.
Detailed description
Purpose The purpose of the study is to describe early predictors and to develop a prediction tool that accurately identifies the need for mechanical ventilation (MV) in pneumonia patients with hypoxemic acute respiratory failure (ARF) treated with high-flow nasal cannula (HFNC). Materials and methods This is a 4-year prospective observational 2-center cohort study including patients with severe pneumonia treated with HFNC. High-flow nasal cannula failure was defined as need for MV. ROX index was defined as the ratio of pulse oximetry/fraction of inspired oxygen to respiratory rate.
Interventions
PROCEDUREmechanical ventilation
Sponsors
Hospital Universitari Vall d'Hebron Research Institute
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* diagnosis of acute respiratory failure secondary to pneumonia receiving HFNC therapy
Exclusion criteria
* younger than 18 years old * indication for mechanical ventilation at ICU admission * limitation of therapeutic effort
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| prediction of need for mechanical ventilation using ROX index | through study completion, an average of 1 year | participants will be followed during their stay in the ICU registering the days with HFNC treatment and their need or not for mechanical ventilation. |
Outcome results
None listed