Arrhythmia, Obstructive Sleep Apnea
Conditions
Keywords
Hypoxia, Perioperative outcomes
Brief summary
Higher risk of cardiac and respiratory post-operative events is observed in patients with unrecognised Obstructive Sleep Apnea (OSA). The efficiency of a simple method of OSA screening by analysing ventilation with measurement of nose pressure and nocturnal hypoxemia (oxygen desaturation index) will be assessed. These sleep respiratory analyses will be compared with the research of arrhythmia, in order to show if they are linked to the hypoxemia events. Aggravation of nocturnal respiratory disorder and higher incidence of cardiac and respiratory postoperative complications will be assessed in OSA patients.
Interventions
OTHERMeasure of ODI and heart rhythm
Record nocturnal respiratory and cardiac parameters before and after surgery.
Sponsors
AGIR à Dom
University Hospital, Grenoble
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
45 Years to 99 Years
Healthy volunteers
Yes
Inclusion criteria
* orthopaedic, urologic, vascular, digestive surgery * under general anaesthesia or sedation * age \> 45 years old * STOP-BANG score\>3
Exclusion criteria
* Head and neck surgery, planned prolonged mechanical ventilation after surgery (\>24h) * Severe COPD * Post-operative ICU planned * Diagnosed OSA or other sleep disorder breathing
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in heart rhythm troubles linked to hypoxemia events | Before surgery and at first and third night after surgery | Heart rhythm troubles will be assessed 3 times: * First time = baseline assessment, during one night before surgery * second assessment will occur during the first night after surgery * last assessment will take place during the third night after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in severity of OSA defined by the oxygen saturation index | Before surgery and at first and third night after surgery | OSA will be assessed 3 times: * First time = baseline assessment, during one night before surgery * second assessment will occur during the first night after surgery * last assessment will take place during the third night after surgery oxygen saturation index \> 10 mandatory for the study oxygen saturation index \> 40 : result qualified severe |
| Aggravation of cardiac events linked to hypoxemia | After surgery from night 1 to night 15 maximum | — |
| Change from baseline OSA prevalence and cardiorespiratory complications after surgery | Before surgery and at first and third night after surgery | — |
Outcome results
None listed