Applications of MRI in Kidney Disease

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02832505

Enrollment

Registered

2016-07-14

Start date

2025-10-30

Completion date

2028-08-30

Last updated

2025-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease, End-stage Kidney Disease

Brief summary

This study has two major purposes: 1. To test developed multiple anatomic and functional MRI methods; 2. To evaluate the potentials of these MRI methods in the diagnosis, prognosis, and monitoring of the progression of renal dysfunction. These purposes will be achieved by performing pilot studies with cohorts of patients.

Detailed description

This study is observational with no intervention applied for the patients. In this study, multiple anatomic and functional MRI methods will be performed with three cohorts of patients. In addition to anatomic MRI methods, non-contrast enhanced functional MRI methods will also be applied to evaluate tissue perfusion and vascular reactivity in these patients.

Interventions

OTHERNo intervention but only observational

This study is a cross-sectional and observational MRI study with three cohorts of patients, and no interventions will be applied.

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

45 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

1. English-speaking as primary language 2. Able to complete an approximately 75 to 90 minute cognitive and/or physical tests 3. Capable to consent to studies

Exclusion criteria

1. Acute psychiatric illness that would impede cognitive testing 2. Active chemical dependence, such as alcohol, narcotics or other drugs 3. Legally blind or unable to complete cognitive tests due to visual loss or deafness 4. Renal transplant recipient at time of screening or baseline 5. Severe CI unable to complete the Modified Mini-Mental State Examination \[3MSE\] 6. Chronic and acute pulmonary disease

Design outcomes

Primary

Measure	Time frame	Description
MRI measured perfusion for each patient group	Baseline	MRI measurements will be summarized for each patient group by using mean and standard deviation or standard error.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026