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A Study of Structure and Function of Radial Artery After Transradial Coronary Intervention

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02831322
Enrollment
600
Registered
2016-07-13
Start date
2016-07-10
Completion date
2017-10-01
Last updated
2023-02-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intervention, Transradial

Keywords

Transradial, flow-mediated vasodilation

Brief summary

Several approaches have been proposed to reduce the risk of RAO, including anticoagulation, immediate postprocedural sheath removal, and a small sheath/radial artery ratio. Doppler ultrasound examination showed that interrupted blood flow in RA tend to occur in the proximal end rather than distal part of the artery,which was ignored by a majority of interventional cardiologists. Different insights into occlusion location may lead to different options of sheath materials, models, catheters and puncture access. Thus, the investigators designed this present study to explore the reason of radial artery endothelial dysfuction and damage and occlusion location by flow-mediated dilation (FMD) to determine the suitable method to reduce occlusion risk during TRI.

Interventions

PROCEDUREPercutaneous coronary intervention

Percutaneous coronary intervention was a nonsurgical technique for treating obstructive coronary artery disease

Sponsors

The First Hospital of Qinhuangdao
Lead SponsorOTHER_GOV

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes

Inclusion criteria

* admitted for transradial catheterization.

Exclusion criteria

* femoral access, arterial circulatory disease, pathological Allen tests, decompensated heart failure, chronic renal failure

Design outcomes

Primary

MeasureTime frameDescription
radial artery occlusion6 monthradial artery occlusion was the absence of a flow signal by Doppler ultrasound examination

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026