Carotid Artery, External
Conditions
Keywords
External carotid artery, Facial artery, Lingual artery, Superior thyroid artery, Internal maxillary artery, Phase-contrast MRI, Rate of flow, Superficial temporal artery
Brief summary
The phase-contrast MRI offers the advantage to combine precisely vascular flow measurements data with morphological images. Even if the anatomy of the external carotid artery is well known, data obtained through Phase contrast MRI could permit to progress in several fields of cranio-maxillofacial surgery as for example arteriovenous malformations,radionecrosis, head and neck micro-reconstructive surgery. The aim of this study is to establish and develop Phase-contrast MRI sequences for vascular flow characterization branches of the external carotid artery in healthy patients and in pathological cases.
Interventions
DEVICEMagnetic Resonance Imaging (MRI),
Magnetic Resonance Imaging (MRI) of flow using phase contrast (PC) methods
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* group 1 : healthy volunteer * group 2 : X-Ray treatment antecedent (at least 50 grays and older than one year) * group 3 : antecedent of embolization of branches of external carotid artery * group 4 : antecedent of muscular free flap surgery (older than one month) * free and informed consent
Exclusion criteria
* group 1 : facial pathology, antecedent of facial injury, antecedent of X-Ray treatment in head and neck localisation, antecedent of head and neck cancer * group 2 : antecedent of surgery for head and neck cancer or for vascular disease * group 3 : antecedent of surgery for head and neck cancer or for vascular disease ; antecedent of X-Ray treatment. * group 4 : antecedent of surgery for head and neck cancer or for vascular disease ; antecedent of X-Ray treatment or embolization * patient with guardianship or trusteeship * MRI cons-indications * pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measurability of flow 1 | 1 hour | flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the maximum speed |
| measurability of flow 2 | 1 hour | flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the minimum speed |
| measurability of flow 3 | 1 hour | flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the average speed |
| measurability of flow 4 | 1 hour | flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the maximum flow rates |
| measurability of flow 5 | 1 hour | flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the minimal flow rates |
| measurability of flow 6 | 1 hour | flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the medium flow rates |
Countries
France
Contacts
CONTACTStéphanie DAKPE, MD
PRINCIPAL_INVESTIGATORBernard DEVAUCHELLE, MD, phD
Amiens University Hospital
Outcome results
None listed